A 36-year-old woman from Ootischenia died in Wednesday afternoon’s crash near Genelle.
The crash happened at 2:15 pm near Courtesy Road and Highway 22.
She was heading south on the highway in a Honda Civic and crossed over the centre line.
The Honda collided sideways with an oncoming Chevrolet Ventura mini-van driven by a 24-year-old woman from Salmo.
The driver of the Honda died at the scene.
The three occupants in the Ventura were taken to hospital with serious, life-threatening injuries.
RCMP is continuing their investigation with the BC Coroners Service to determine what caused the accident.